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Vernon L Tesh Selected Research

Shiga Toxin (Shigella Toxin)

10/2017Shiga Toxins Induce Apoptosis and ER Stress in Human Retinal Pigment Epithelial Cells.
3/2016Shiga Toxins as Multi-Functional Proteins: Induction of Host Cellular Stress Responses, Role in Pathogenesis and Therapeutic Applications.
1/2016Shiga Toxins Activate the NLRP3 Inflammasome Pathway To Promote Both Production of the Proinflammatory Cytokine Interleukin-1β and Apoptotic Cell Death.
6/2010Distinct physiologic and inflammatory responses elicited in baboons after challenge with Shiga toxin type 1 or 2 from enterohemorrhagic Escherichia coli.
11/2005Lipopolysaccharide upregulates renal shiga toxin receptors in a primate model of hemolytic uremic syndrome.
1/2005Reduced nitric oxide bioavailability in a baboon model of Shiga toxin mediated hemolytic uremic syndrome (HUS).
1/2005Chemokine expression in the monocytic cell line THP-1 in response to purified shiga toxin 1 and/or lipopolysaccharides.
5/2004Regulation of proinflammatory cytokine expression by Shiga toxin 1 and/or lipopolysaccharides in the human monocytic cell line THP-1.
2/2003Response to Shiga toxin 1 and 2 in a baboon model of hemolytic uremic syndrome.
12/2002Prophylactic heparinization is ineffective in a primate model of hemolytic uremic syndrome.
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Vernon L Tesh Research Topics

Disease

14Hemolytic-Uremic Syndrome
11/2022 - 07/2001
6Acute Kidney Injury (Acute Renal Failure)
11/2022 - 05/2004
5Colitis
11/2022 - 12/2002
4Infections
12/2013 - 05/2004
3Inflammation (Inflammations)
11/2020 - 06/2010
2Neoplasms (Cancer)
01/2016 - 03/2010
2Necrosis
01/2016 - 07/2001
2Disease Progression
01/2012 - 09/2010
2Diarrhea
01/2005 - 05/2004
2Thrombocytopenia (Thrombopenia)
02/2003 - 07/2001
2Hemolytic Anemia
02/2003 - 07/2001
2Thrombotic Microangiopathies
12/2002 - 07/2001
1Blindness (Hysterical Blindness)
10/2017
1Toxemia
06/2010
1Bacillary Dysentery (Shigellosis)
06/2010
1Intestinal Diseases (Diseases, Intestinal)
01/2010
1Myeloid Leukemia (Leukemia, Myelocytic)
08/2005
1Azotemia
02/2003

Drug/Important Bio-Agent (IBA)

13Shiga Toxin (Shigella Toxin)IBA
10/2017 - 07/2001
8Shiga Toxins (Vero Toxin)IBA
11/2022 - 01/2010
6Virulence Factors (Pathogenicity Factors)IBA
11/2022 - 01/2010
3CytokinesIBA
11/2020 - 12/2013
3LipopolysaccharidesIBA
11/2005 - 09/2002
3Shiga Toxin 1 (SLT-I)IBA
08/2005 - 09/2002
2Proteins (Proteins, Gene)FDA Link
11/2020 - 01/2012
2ChemokinesIBA
12/2013 - 04/2013
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2010 - 08/2005
2FibrinIBA
12/2002 - 07/2001
1Retinal Pigments (Pigments, Visual)IBA
11/2020
1Interleukin-8 (Interleukin 8)IBA
04/2013
1Messenger RNA (mRNA)IBA
04/2013
1Biomarkers (Surrogate Marker)IBA
04/2013
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
04/2013
1Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA
04/2013
1Annexin A5IBA
01/2012
1CaspasesIBA
01/2012
1Cytochromes c (Cytochrome c)IBA
01/2012
1RNA (Ribonucleic Acid)IBA
01/2012
1AntitoxinsIBA
06/2010
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
06/2010
1Dual Specificity Phosphatase 1IBA
06/2010
1Mitogen-Activated Protein KinasesIBA
06/2010
1Cytotoxins (Cytolysins)IBA
06/2010
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
06/2010
1Drinking WaterIBA
01/2010
1ProcalcitoninIBA
04/2006
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
08/2005
1Death Domain ReceptorsIBA
08/2005
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2005
1Hemoglobins (Hemoglobin)IBA
01/2005
1EndotoxinsIBA
05/2004
1Interleukin-6 (Interleukin 6)IBA
02/2003
1Heparin (Liquaemin)FDA LinkGeneric
12/2002
1Epoprostenol (Prostacyclin)FDA LinkGeneric
10/2002
1von Willebrand FactorIBA
09/2002
1glycolipid receptorIBA
07/2001

Therapy/Procedure

1Therapeutics
01/2012
1Intravenous Administration
09/2002